The Mozart Effect—the idea that listening to Mozart can enhance cognitive abilities—gained widespread popularity but lacks strong scientific backing, especially in the context of autism therapy. While early studies suggested short-term spatial reasoning benefits, later research failed to confirm long-term cognitive improvements. In contrast, music therapy, an evidence-based, interactive approach, has shown significant benefits for individuals with autism, aiding in communication, emotional regulation, social engagement, and sensory processing. This article critically examines the myths surrounding the Mozart Effect, highlights the neuroscience behind music’s impact on autism, and explores how personalized, structured music therapy can create meaningful improvements in autistic individuals’ lives. Ultimately, while passive listening to Mozart may be enjoyable, real therapeutic progress comes from actively engaging with music in tailored, structured ways.