In understanding autism spectrum disorder (ASD), it’s vital to recognize the often accompanying co-occurring conditions and comorbidities. These additional challenges, including ADHD, anxiety disorders, depression, intellectual disabilities, sensory sensitivities, gastrointestinal issues, epilepsy, sleep disorders, language impairments, and motor coordination difficulties, significantly impact the individual’s well-being and daily functioning. Identifying these conditions involves comprehensive screening tools, clinical observation, and input from caregivers. Treatment typically involves a multidisciplinary approach tailored to the individual’s specific needs, incorporating evidence-based interventions such as medication, therapy, and behavioral supports. Ongoing monitoring is crucial to address changes in behavior and ensure optimal long-term outcomes, emphasizing the importance of comprehensive assessment and intervention strategies in supporting individuals with ASD.