Autism, once viewed primarily as a brain-based disorder, is increasingly understood as a whole-body condition shaped by gut health, immune function, and environmental triggers. Mounting research points to a powerful triad—the gut-brain-immune axis—where microbial imbalances, intestinal permeability (“leaky gut”), and autoimmune responses may underlie many behavioral and cognitive symptoms. By addressing root causes through integrative approaches—such as dietary therapy, microbiome restoration, immune modulation, and caregiver education—families and practitioners are witnessing transformative changes. Grounded in science and compassion, the path forward lies in restoring systemic balance, honoring neurodiversity, and building community ecosystems where every individual can thrive with dignity and vitality.